Ninewells Hospital & Medical School, Dundee, DD1 9SY

Antipsychotic augmentation in OCD: optimal doses

We discuss the issue of higher-than-needed doses of antipsychotic medication for augmentation in OCD. This can cause side effects. We briefly review the evidence to support the use of Risperidone in treating OCD and look at typical doses. We go on to make some recommendations for optimum doses of Risperidone. Background In the last year, …

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Evidence review: N-acetylcysteine for OCD

Introduction N-acetylcysteine is thought to regulate glutamate neurotransmission in the brain, and also acts as a potential anti-oxidant. It increases the amount of extracellular glutamate by enhancing the activity of the¬†cystine/ glutamate transporter. There are a number of other drugs that are sometimes used to treat OCD that act on glutamate. These include: Memantine; Riluzole, …

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